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pentobarbital will lessen the level or impact of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will minimize the extent or impact of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives can be min